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KMID : 0363220170550060351
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Korean Journal of Dermatology
2017 Volume.55 No. 6 p.351 ~ p.355
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A Case of Clear Cell Papulosis Misdiagnosed as a Negative for Carcinoembryonic Antigen and Literature Review
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Lee Mi-Hye
Kim Young-Jae
Lee Woo-Jin
Won Chong-Hyun
Chang Sung-Eun
Choi Jee-Ho
Moon Kee-Chan
Lee Mi-Woo
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Abstract
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Clear cell papulosis (CCP) is a rare skin condition characterized by asymptomatic multiple hypopigmented maculopapules distributed primarily on the lower aspect of the abdomen or along the milk lines in young children. The characteristic histological feature of CCP is the presence of clear cells scattered among basal keratinocytes. We describe the case of a 3-year-old girl with clear cell papulosis. Immunohistochemical staining results were variable based on the different kinds of CEA antibodies. Immunostaining specification of CEA glycoproteins may provide a clue for the differential diagnosis of clear cell papulosis with other diseases such as primary extramammary Paget`s disease
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KEYWORD
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Clear cell papulosis, Immunohistochemistry, Carcinoembryonic antigen
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